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J.HartmannB.et al (2003)

Second, most of the dosing conventions people cite come from animal studies and clinical experience, not from large human trials that nailed down the optimal dose, route, and duration

It is also effective for diabetic patients managing type 2 diabetes or insulin resistance, offering extra support with blood sugar balance

Treatment resistance was defined through a composite of indicators including requirement for escalation of medical therapy, progression to surgical intervention, need for CSF diversion procedures, or optic nerve decompression/ONSF necessity

Comparison of the effects of 10 GLP-1 RA and SGLT2 inhibitor interventions on cardiovascular, mortality, and kidney outcomes in type 2 diabetes: a network meta-analysis of large randomized trials