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PBS, phosphate buffered saline

A systematic review of evidence found that there was no significant difference in the incidence of post-herpetic neuralgia (pain persisting for at least 120 days after onset of rash) after four or six months in patients initially treated with either oral aciclovir or famciclovir compared to placebo

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The results show that the spinal dorsal horn of the DNP rats activated microglia and astrocytes, but SEMA therapy markedly reduced this activation by correcting the pathological alterations