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oxidative stress, calcium overload, and glutamate toxicity may also lead to energy deficiencies, forming a vicious cycle with -synuclein accumulation

Another crucial point is that, when an individuals antioxidant defense system is weak or saturated, inhaling additional ROS or other reactive metabolites produced by the biotransformation of chemicals in tobacco smoke can increase the amount of oxidative stress caused by the gas-phase and tar-phase derived ROS (60)

Understanding the interaction between food choices and medication effects empowers patients to make informed decisions about their diet throughout treatment