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Youth-onset type 2 diabetes mellitus: an urgent challenge

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Current research is primarily based on mouse models, necessitating the establishment of a tiered evaluation system from rodents to large mammals (such as pigs and monkeys) to validate motor controllability, long-term biosafety, and scalable drug delivery efficiency in large animals

Lumbar spine BMD tended to decrease in the LC group after the 3-month intervention (p = 0.069), but no other changes in BMD were noted (Table 3)

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