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FTO rs9939609 and MC4R rs17782313 variants correlate with hunger pathway sensitivity and satiety signaling, affecting how effectively semaglutide suppresses appetite for individual patients

Patients using GLP-1 receptor agonists were also more likely to have microvascular complications and a history of depression

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36 Dedicated Heart Failure Trials The STEP-HFpEF, STEP-HFpEF DM and SUMMIT trials represent key advances in the evaluation of GLP-1RAs in the treatment of HF

Rotate injection sites weekly to prevent lipodystrophy, a condition where repeated injections in the same spot cause tissue changes that affect absorption