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Zhao F, et al

Induction of differentiation by granulocyte and granulocyte macrophage colony stimulating factor and cytosine arabinoside in the human myeloid leukemic cell line KG 1

Mechanistically, SWT activates the Nrf2/HO-1 pathway, boosts antioxidant enzyme expression such as SOD, and attenuates lipid peroxidation, while simultaneously promoting angiogenesis via the STAT3/HIF-1/VEGF cascade, collectively improving follicular microenvironment and reproductive capacity [161]

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Secondly, IGF-1s molecular structure and known actions with emphasis on metabolic actionswhich will be discussed in detail