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A 2% niacinamide, 23% TXA, 4% -arbutin, and 4% ferment filtrate serum and a 4% niacinamide, 3% -arbutin, 1% bisabolol, and 0.05% retinaldehyde cream were also effective in treating hyperpigmentation issues [130]

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54,55 Similarly, in neurodegenerative diseases, enhancing both HSP70 and autophagy could provide a synergistic approach to clearing protein aggregates

Ethics declarations Conflict of interest Sun-Ki Kim, Managing Editor of Food Science and Biotechnology , was not involved in the editorial consideration of this manuscript