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"The effects of copper tripeptide and tretinoin on photodamaged skin." Cosmet Dermatol

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Because cytochrome P450 reductase (CYPOR) is highly expressed in HepG2 cells and in primary hepatocytes (Schulz et al

According to guidelines, opioid therapy should be initiated as immediate-release formulations and used first on demand for symptom control, at the lowest dose to achieve acceptable analgesia, that can be shared with the patients expectations (12, 24)