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Follow-up reports indicate stabilization of cartilage degradation and, in some cases, improvement of joint cartilage

When the FDA places a peptide in a restricted or high-risk category [known as Category 2], it is explicitly signaling that it has identified safety concerns and that enforcement discretion does not apply. But, as Hajduczok notes, just because something is not FDA-approved doesnt mean its illegal to compound, but the restricted peptides should not be compounded

Ozempic was designed by Novo Nordisk to treat type 2 diabetes and was approved by the Food & Drug Administration (FDA) in 2017

D.PhillipsM.AsztalosB.BittmanR.et al (2011)

Patients should be encouraged to report any changes in mood or behavior to their healthcare provider and drug safety authority [25]