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Mol Metab 2021;46:101102.ArticlePubMed 68

Severe caloric restriction accelerates muscle loss and may impair hormonal function

Your individual responseincluding the severity and duration of constipationdepends on dose, formulation, baseline gut health, hydration status, and genetic factors affecting how your body processes GLP-1 signaling

If youre past those windows, skip the missed dose and resume on your next scheduled day