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The NF-B signal can be triggered by multiple stimuli, including cytokines (e B pathway impairs protein C anticoagulation mechanism and promotes coagulation in endotoxemic mice

This discrepancy may be due to paxillins inherent FA targeting through the four highly conserved LIM domains at its C-terminus, which localize the protein to FAs by either direct interaction with -integrin tails or other intermediate binding partners 42

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Conversely, when too much collagen is produced, hypertrophic or keloid scars develop, marked by raised, growth-like scars