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In terms of blood pressure management, GLP-1 RAs modulate the renin-angiotensin-aldosterone system (RAAS), reduce vascular resistance, and improve vascular relaxation, effectively lowering SBP 39,40,41

Research protocols typically begin at 0.25mg daily for 35 days to assess tolerance before increasing to 0.51.0mg maintenance dose

[DOI] [PMC free article] [PubMed] [Google Scholar] 16.Sanyal AJ, Kaplan LM, Frias JP, et al

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As observed, the trend line for the CON was consistently approximately twofolds higher than the corresponding SZ and BP trend line when considering total GSH level over the entire age distribution