2.5 mg to 15 mg maintenance Mean weight loss (standard dose) Wegovy: ~13.7% at 72 weeks (SURMOUNT-5) Mounjaro: ~20.2% at 72 weeks (SURMOUNT-5) Available in Ireland Wegovy: Yes - private prescription Mounjaro: Yes - private prescription HSE reimbursement Wegovy: Not yet (NCPE review ongoing) Mounjaro: Not yet Access and Cost in Ireland in 2026 Both Wegovy and Mounjaro are available in Ireland on private prescription
Valencio ACJ, Antunes AB, Fonseca L, et al
Zhang Y., Han P., Wu N., He B., Lu Y., Li S., Liu Y., Zhao S., Liu L., Li Y
Additionally, upregulated Ras-RAF-MEK pathway expression may enhance cancer cell sensitivity to ferroptosis by modulating VDAC2/3 function and increasing ROS generation (40)
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