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Giacomini KM, Huang SM, Tweedie DJ et al (2010) Membrane transporters in drug development

Han SW, Lee SH, Kim JH, Lee JJ, Park YH, Kim S, Nho K, Sohn JH

In this Perspective, we summarize key trends in peptide drug discovery and development, covering the early efforts focused on human hormones, elegant medicinal chemistry and rational design strategies, peptide drugs derived from nature, and major breakthroughs in molecular biology and peptide chemistry that continue to advance the field

In the past five years, these drugs have moved from diabetes clinics to mainstream medicine and for good reason

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