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NADPH-replete conditions, closed bars) compared to GMM with ammonium as a sole nitrogen source (open bars)

Notably, the effect of CR and DL feeding on Cysteine and Methionine metabolism was observed in both plasma and brain samples of female, but not male, 3xTg mice, with similar effects on most of the metabolites detected despite the pathway being upregulated in the brain and downregulated in the plasma (Fig

To better understand the effects of ABHD11 inhibition in CD8 + T cells, we undertook RNA-seq analysis following ML226 treatment

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