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Fast facts Product: Wegovy pill (oral semaglutide) Approval: FDA-approved as the first oral GLP-1 for weight management Provider: Available via GoodRx at ~70,000 US pharmacies Access: Cash-pay option with optional telehealth support through GoodRx for Weight Loss Clinical trial results support oral semaglutide approval The approval is linked to results pertaining to both the OASIS trial program and the SELECT trial
doi: 10.1016/j.heliyon.2023.e21431 Summary Keywords L -arginine, meat quality, physiological metabolism, 16S rRNA, metabolomics Citation Liu C, Yang Y, Wang M, Jiang W, Du Y, Hao Z, Chen L, Zhu K, Liu B, Niu L, Zhao Y, Wang Y, Gan M, Shen L and Zhu L (2024) Effects of L -arginine on gut microbiota and muscle metabolism in fattening pigs based on omics analysis
One area of important future research with regard to developing more efficacious GLP-1-based weight-loss therapies is to dissociate the neural circuits mediating GLP-1R-associated anorectic effects from nausea and malaise