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It also tends to stabilize over time

In addition, the levels of proinflammatory factors (such as IL-6, TNF-, and IL-1) are increased in the aged hematopoietic niche, and these factors can disrupt the differentiation bias and functional decline of HSCs

Trends Pharmacol Sci (2018) 39(5):51324

NICE recommends monitoring response to treatment through clinical assessment and blood tests as appropriate

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