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B12 absorption requires a protein called intrinsic factor , produced in the stomach

Most public attention has been on fat loss, but separate animal work has also looked at joint and cartilage research

It's also important to let us know if you have any allergies (especially to cobalt or B12), or if you have Leber's disease, kidney problems, or are pregnant or nursing

Tran will conduct a comprehensive evaluationincluding a review of your medical history and your current symptomsto determine if you may benefit from B12 supplementation

Here's the TL;DR on vitamin timing: while there is no official medical advice dictating that you should take vitamin supplements at a specific time of day to improve their efficiency, there is quite a lot of research showing that avoiding some vitamin supplements at particular times (or more accurately, with particular meals) can improve absorption, or that taking some vitamins alongside food can reduce the risk of adverse side effects