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Your provider will determine your maintenance dose based on two primary factors: Effectiveness: Are you losing weight at a safe, steady rate (typically 12 pounds per week)

Even so, prior studies suggest that up to 65 % of patients discontinue them within a year, and discontinuation has been associated with weight regain and reduced cardiometabolic benefits

Type 2 diabetes, depression, anxiety, sleep disorders, thyroid dysfunction, and numerous other medical conditions can all cause brain fog independently

Furthermore, endotoxemia produced by intestinal dysbiosis may trigger the low-grade inflammation observed in obesity and IR [63]

This seems like a fairly representative population of patients in whom we might want to use this medication