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Newer data, including the 2025 SEMALEAN study, shows that lean mass can be largely preserved when adequate protein, resistance training, and body composition monitoring are built into the protocol

They don't establish that GLP-1s should be avoided - they establish that a musculoskeletal protection plan is a necessary component of responsible GLP-1 therapy

If you miss a dose by fewer than 5 days, take it as soon as you remember and resume your normal weekly schedule

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