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Additionally, these agents help regulate postprandial glucose by suppressing hepatic glucose production and delaying gastric emptying
Additionally, it may affect gastric emptying and improve insulin sensitivity, contributing to weight loss benefits
The table reveals why researchers find this combination theoretically interesting
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15 Phase II trials targeting MASH have shown that treatment with SEMA 0.4 mg daily for 72 weeks resulted in more patients with liver fibrosis stage F2/F3 achieving improvement in MASH without progression of liver fibrosis (odds ratio = 6.87, 95% CI = 2.6017.63) compared to placebo
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