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Copper is an essential trace mineral involved in a wide range of enzymatic processes in biological systems, including collagen synthesis, superoxide dismutase activity, and angiogenesis

However, high doses can cause: Stomach upset or diarrhea Kidney stones in susceptible individuals Iron absorption issues if you have iron overload conditions People with kidney problems should be cautious with high-dose vitamin C supplements

Examples of drugs and their different bioavailability: Oxycodone has a bioavailability of about 6087% when administered orally

Vester U, Schubert M, Offner G, Brodehl J (2000) Distal myopathy in nephropathic cystinosis