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Despite these observations, additional research is needed to chemically modify methylene blue to improve its uptake into the brain and include larger and more diverse patient populations

These excipients, such as polysorbate 20, glycine, sucrose, and, mannitol protect the product from clumping, structural changes, and, denaturing over time

To prolong plasma half-life and improve drug delivery, butyrate and sorafenib were co-encapsulated within antibody-functionalized mPEG-PLGA-PLL nanoparticles, which significantly reduced sorafenib-induced liver injury and suppressed hepatocellular carcinoma progression [121]

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Reusing syringes, even for the same patient, increases infection risk and reduces injection comfort