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Repeated trauma such as onychotillomania, onychophagia, or friction from footwear may also cause it.11 Medications such as phenolphthalein, antimalarials, minocycline, gold salts, zidovudine, and some chemotherapeutic agents may also induce changes in nail coloration.1 Inflammatory disordersLichen striatus An inflammatory dermatosis, usually unilateral, of unknown cause