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All studies were 68 weeks in duration

Quick Answer: Injectable semaglutide generally provides greater blood sugar reduction and weight loss than oral tablets, but oral semaglutide offers a needle-free alternative for type 2 diabetes management

van Bloemendaal L, IJzerman RG, ten Kulve JS, Barkhof F, Konrad RJ, Drent ML, et al

GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide) are the two hormones mimicked by Mounjaro and are responsible for reduced appetite and a prolonged feeling of fullness

People with preexisting GI symptoms may be more prone to discomfort or intolerance, though responses vary, and formal evidence is limited