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doi: 10.4093/dmj.2025.0220

Rybelsus works by enhancing insulin secretion in a glucose-dependent manner, slowing gastric emptying, and reducing appetitemechanisms that generally improve blood glucose control rather than worsen it

Potential Liver Health Benefits Non-alcoholic fatty liver disease (NAFLD) is a growing health concern, particularly among individuals with obesity and diabetes

For example, Rybelsus (semaglutide tablets), the first oral GLP-1 approved for type 2 diabetes, has demonstrated meaningful weight loss in clinical studies, although it currently requires strict administration guidelines (empty stomach, limited fluid intake before and after dosing)

When to talk to your doctor about semaglutide bloating Most semaglutide bloating is manageable with the dietary and lifestyle strategies described above