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Conversely, if you take your injection 12 days late, you might notice a brief return of hunger or slightly less appetite control the day or two before your injectionthis is your body's way of signaling that medication levels are dropping as you approach your next dose

This is risky for several reasons: Wrong patient selection, such as people with pancreatitis, gallstones, or severe kidney disease using them without screening Rapid, unsupervised dose escalation No monitoring of kidney, liver, pancreatic, or eye status Complications seen with unsupervised use include pancreatitis, dehydration-induced acute kidney injury (especially in hot Indian summers with vomiting or diarrhoea), and even diabetic ketoacidosis in susceptible individuals

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