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Inhibition of CDO1 activity restores the level of GSH in cells, prevents the production of ROS, reduces the level of lipid peroxidation, and ultimately inhibits the occurrence of ferroptosis

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[15] The resulting DSIP-CBBBP construct outperformed unmodified DSIP on neurotransmitter restoration in the mouse model, which is the clearest available statement of the problem: the peptide had to be rebuilt to get where it was supposed to act

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The original research team headed by Dr