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revealed that, although changes within the phylum Firmicutes are heterogeneous, butyrate-producing generasuch as Faecalibacterium, Roseburia, and Coprococcusare significantly reduced, whereas Proteobacteria expanded and Bacteroidetes decreased (Qin et al., 2012), The number of Bifidobacterium (Li et al., 2023) decreased, while randomized studies suggested an increase in Bacteroides (Zhang et al., 2025)

321 Some existing drugs are being repurposed to treat MAFLD by promoting or inhibiting ferroptosis