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Patients may also experience fatigue or dizziness, especially if not staying well hydrated

At 48 weeks with the 12mg dose: systolic blood pressure dropped 7.4 mmHg, triglycerides fell 30%, HDL cholesterol increased 8%, and HbA1c decreased 0.4% even in participants without diabetes

These changes will affect Novos blockbuster weight-loss therapy Wegovy, as well as its older GLP-1 drug Saxenda, according to the FDAs announcement on Tuesday

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A key role for transmembrane prolines in calcitonin receptor-like receptor agonist binding and signalling: implications for family B G-protein-coupled receptors