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Anything that attempts to restore the tumour oxygen levelssuch as hypoxia-activated prodrugs or oxygenation therapiescould further augment lipid peroxidation and thus maximize therapies over-demand for oxidative stress [277]

Most side effects are transient and manageable with appropriate intervention

Transfection was carried out using Lipofectamine 3000 Kit on cells at 50% confluence for 6 hours, followed by protein extraction 48 hours post-transfection

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Dual agonists that activate both GLP-1 and GIP receptors have been shown to provide more pronounced weight loss, better glycemic control, and better metabolic outcomes compared to GLP-1 RAs alone