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Skin laxity is another concern with weight loss exceeding 15-20% of body weight

Thirdly, GI symptoms are common in healthy adults, with a greater frequency in individuals with diabetes even if they are not using a GLP-1RA, and these symptoms characteristically fluctuate (27)

New England Journal of Medicine, 393(1), 2636

In March 2024, the FDA further approved Wegovy to reduce the risk of major adverse cardiovascular events (cardiovascular death, non-fatal myocardial infarction, or non-fatal stroke) in adults with established cardiovascular disease and either obesity or overweight