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A randomized, controlled trial of liraglutide for adolescents with obesity

Clinical trials have shown that when combined with lifestyle changes, patients using GLP-1 medications can achieve significant weight lossoften ranging from 15% to 20% of their total body weight over a year

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Furthermore, polymeric nanoparticles can be functionalized with ligands, antibodies, or targeting molecules to direct their cargo toward specific cells or tissues, thereby reducing off-target effects and improving vaccine efficacy [112]