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The inflammation pattern is mechanistically predictable: IGF-1 LR3's reduced binding affinity for IGFBPs means higher local concentrations at injection sites, triggering immune response and localized edema

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Glutamate participates in diverse physiological processes, such as developmental plasticity and long-term potentiation as well as brain diseases: epilepsy, stroke, amyotrophic lateral sclerosis, Alzheimers disease, Parkinsons disease and schizophrenia (3)

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