glutathione and antibiotic interactions Glutathione-Mediated Conjugation of Anticancer Drugs: An Overview of Reaction Mechanisms Biological Significance for Drug Detoxification and Bioactivation A locally activatable sensor for

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Since mitochondria do not have the enzymes involved in the synthesis of GSH, all the GSH found in the mitochondrial compartment comes from the cytosol

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It has indeed been shown that, when available for the host cells, GSH plays an important role in the protection of cells against oxygen radicals, detoxification and metabolisation of various endo- and exogenous compounds, cell cycle regulation, cell signaling and apoptosis 16,50,51,52