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The presence of small amounts of sugars (like sucrose) helps stabilize the peptide, as their hydrogen bonds mimic those of water and reduce moisture-related collapse
Zhang HL, Lv C, Li ZH et al (2023) Analysis of aptamer-target binding and molecular mechanisms by thermofluorimetric analysis and molecular dynamics simulation
Furthermore, it is likely that the optimal ratio of receptor agonism across target receptors varies between individuals
2001;7(6):3959 discussion 399400
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