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I will tell my patients to shoot for 1.2 g to 1.6 g of protein per Kg of body weight while they are losing weight on a GLP-1

10.3389/fmed.2015.00052 Front

In the Diabetes Prevention Program (DPP) and Diabetes Prevention Program Outcomes Study (DPPOS), metformin group showed 2.7% weight loss from baseline compared to placebo at 1 year, and this effect was maintained at 10 years [23]

We however think that GLP-1RAs should be avoided in people with HF with reduced ejection fraction until robust evidence of benefit is generated in this group