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Additionally, it is believed that the PPG neurons are not the only source of GLP-1 in the brain, as gut-derived GLP-1 has been implicated in satiety studies to exert its effects on the brain as well [52]

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Research that encompasses all the different microflora, nematode and earthworm communities in the same study is needed because these organisms occur together and interact in the soil and shifts in one community may affect the biological or trophic balance