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The specific thresholds that should prompt dose reduction or discontinuation include: ALT or AST elevation exceeding 3 times the patient's baseline value, new or worsening coagulopathy (INR increase of 0.5 or more from baseline), albumin decline below 2.5 g/dL, or new clinical signs of hepatic decompensation such as worsening ascites, encephalopathy, or jaundice [5]
Parvin currently serves as co-lead counsel in the related GLP-1 RAs Products Liability Litigation, where patients who took Ozempic, Wegovy, and similar drugs suffered serious gastrointestinal injuries, as well as co-lead counsel in the Elmiron Products Liability Litigation , a nationwide MDL alleging that the drug caused permanent vision injuries
doi:10.1186/1472-6815-2-3