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Two-Year Effects of Semaglutide in Adults with Overweight or Obesity: The Step 5 Trial. Nature News, Nature Publishing Group, 10 Oct

Pathologic fusion of the Ewing gene EWS to WT1 (t(11;22)(p13;q12)( EWS/WT1 )) has been shown to abrogate the tumour suppressor function of WT1 and to generate an oncogenic chimeric protein capable of binding and activating the IGF-1R promoter (Karnieli et al, 1996)