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4 Trends in Molecular Medicine (PubMed)Goldstein AL, Hannappel E, Kleinman HK thymosin 4 as an actin-sequestering protein that moonlights to repair injured tissues

While systemic dihexa half life remains one to two hours, CNS concentrations may persist for four to six hours because the peptide is delivered to the target site without requiring blood-brain barrier penetration

doi:10.1007/s13679-023-00527-y Kong F, Wu T, Dai J, et al

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CRediT authorship contribution statement Wentian Lu: Conceptualization, Data curation, Investigation, Methodology, Visualization and Writing - original draft