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Tirzepatide tends to work slightly faster in some patients, with noticeable effects within 2 to 4 weeks

Higher doses could cost as much as $349 a month

Safe alternatives include metformin, SGLT2 inhibitors (empagliflozin, dapagliflozin), DPP-4 inhibitors (sitagliptin, linagliptin), and exenatide immediate-release or lixisenatide, which do not carry thyroid cancer warnings

But much more research is needed to truly understand how effective these practices are and at what dosage

GLP-1-ra and heart failure-related outcomes in patients with and without history of heart failure: an updated systematic review and meta-analysis