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Vitamin B12 plays a crucial role in numerous physiological processes, including cell reproduction, growth, blood formation, and the synthesis of proteins and tissues

Metformin, the medicine in Metformin tablets, can cause a rare, but serious, side effect called lactic acidosis (a build-up of lactic acid in the blood) that can cause death

This is more commonly associated with oral supplementation at higher doses but can theoretically occur with any route of administration

The insurance carriers, like many others across the country will continue to cover the drugs in certain circumstances for individuals with specific underlying medical conditions, as well as offer the coverage through employer-sponsored plans if the plan sponsor opts to continue coverage (with a premium surcharge)

doi: 10.2174/1386207324666210705114058 286 ChenMWangSChenYShenHChenLDingLet al