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Genetic depletion of PPAR efficiently restored the function of DCs and improved the antitumor ability of DCs vaccines (88), however, this study did not explore the underlying mechanism and another research showed that sustained PPAR activation reduced the expression of costimulatory molecules and IL-12 in DCs, ultimately impairing their capacity to prime nave CD4 + T cells (89)

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Give small dogs 0.5 to 2mL, larger dogs 0.5-5mL

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