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Further validations in terms of specificity, sensitivity, and reproducibility in larger populations (including children as well) will be required for these new markers before applications in routine clinical practice

Medical Research Archives, [S.l.], v

(2018) Oridonin enhances the cytotoxicity of 5-FU in renal carcinoma cells by inducting necroptotic death, Biomed

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Indeed, we performed RNA-seq of 5 hyperplastic and 3 normal prostate specimens and found that there was a number of DEGs between hyperplastic prostate and normal prostate, of which the up-expressed matrix-remodeling associated 5 (MXRA5) [9], C-X-C motif chemokine ligand 13 (CXCL13) [10], bone morphogenetic protein 5 (BMP5) [11] and neural epidermal growth factor-like like 2 (NELL2) [12], and the down-expressed glutathione peroxidase 3 (GPX3) ranked at the top and most of them have been reported