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If a product contains synthetic fillers, artificial colors, or GMO-sourced ingredients, those additives may undermine the very health goals you are trying to reach

10.1024/0300-9831.72.6.375 70 ZuckermanT.RoweJ

These root polyphenols were more effective than those from unripe fruits in reducing the levels of pro-inflammatory cytokines and downregulating the mRNA expression of cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (281)

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Generating sufficient safety evidence would require large-scale clinical trials involving thousands of participants