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The FDA-approved injection targets GLP-1 and GIP receptors and causes an average patient to lose 20% of body weight in one year

Farnesoid X receptor agonist decreases lipid accumulation by promoting hepatic fatty acid oxidation in db/db mice

They also help to regulate mood and improve metabolism, making them a valuable tool in weight management and wellness routines

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Phase 2 body composition data from the Lancet Diabetes and Endocrinology substudy showed retatrutide achieving fat mass reductions of 15.2% at the 4mg dose, 26.1% at 8mg, and 23.2% at 12mg, while the proportion of lean mass loss relative to total weight loss remained comparable to other GLP-1 compounds