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The table below provides a summary of these medications along with the mechanism of action, development stage, and key findings (Table 1)

In order to improve outcomes, biphasic scaffolds can be created with a softer upper layer containing chondrogenic factors (e.g., TGF-, chondroitin sulfate) and a stiffer lower layer, often loaded with calcium phosphate, hydroxyapatite, or bone morphogenetic protein (BMP), to provide structural support of the above cartilage layer and to promote osteogenic tissue formation and boney integration

Elastic fibres

Patients should be educated on recognising symptoms such as tremor, sweating, confusion, and palpitations, and advised to carry fast-acting carbohydrates