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If you do not look at the bedtime numbers and continue to titrate the basal insulin upwards, it could lead to a situation where too much basal insulin could cause hypoglycemia, especially if the patient has an unusual normal glucose value at bedtime

Recent literature suggests that central GLP-1 and GIP have a synergistic action on hypothalamic neurons with effects on food intake and body weight (24) ( Figure 2 )

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ECMO is an advanced therapy that supports patients with serious cardiac or pulmonary conditions such as heart attack or pneumonia