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ERAD helps mitigate this burden by degrading these proteins, thereby preventing their aggregation and the subsequent activation of detrimental pathways, such as chronic ER stress, autophagy dysfunction, and apoptotic signaling

In severe cases of BPH, surgical intervention may be necessary, such as transurethral resection, in which excess prostate tissue is removed, enucleation of the prostate and open prostatectomy

She advised also checking for nutritional deficiencies (like iron and B12), environmental exposures and underlying health conditions

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"The basis is around the complexity regarding gender, the norms around payments for women the history of colonialism and how war and conflict can impact the way we see things, like skin colour," she said